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VU 0469381
CAS No. 1062368-49-3
VU 0469381( 1LWY | VU0469381 | ML347 | ML 347 )
Catalog No. M10277 CAS No. 1062368-49-3
A potent, sellective BMP receptor ALK2 antaognist with Ki of 32 nM, with no affinity for ALK3/4/5/6.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
|
| 5MG | 47 | In Stock |
|
| 10MG | 69 | In Stock |
|
| 25MG | 143 | In Stock |
|
| 50MG | 259 | In Stock |
|
| 100MG | 441 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVU 0469381
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, sellective BMP receptor ALK2 antaognist with Ki of 32 nM, with no affinity for ALK3/4/5/6.
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DescriptionA potent, sellective BMP receptor ALK2 antaognist with Ki of 32 nM, with no affinity for ALK3/4/5/6.
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In Vitro——
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In Vivo——
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Synonyms1LWY | VU0469381 | ML347 | ML 347
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PathwayTGF-beta/Smad
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TargetTGFBR
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RecptorALK1|ALK2|ALK3|ALK6
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1062368-49-3
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Formula Weight352.397
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Molecular FormulaC22H16N4O
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Purity>98% (HPLC)
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SolubilityDMSO: 7.1 mg/mL (20 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESCOC1=CC=C(C(C=N2)=CN3C2=C(C4=CC=CC5=C4C=CC=N5)C=N3)C=C1
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Chemical Name5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Engers DW, et al. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3248-52.
2. Engers DW, et al. Probe Reports from the NIH Molecular Libraries Program.
3. Tsugawa D, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):549-58.
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